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Soma and Interaction with other drugs

Product Name Price Order link
Generic soma ( Carisoprodol ) 350mg 30Tabs $45
Generic soma ( Carisoprodol ) 350mg 90Tabs $70
Soma ( Watson Brand ) 350mg 30Tabs $55
Soma ( Watson Brand ) 350mg 90Tabs $75

Your risk for developing side effects may be increased if you combine alcohol with Soma. Interactions may also occur if you take Soma together with medications such as barbiturates, narcotics, sleep medicines, and benzodiazepines. Other Soma drug interactions may also affect the level of Soma in the blood, which may or may not change the effectiveness of the medication.

An Overview of Soma Interactions

Soma® (carisoprodol) can potentially interact with several other medications. Some of these medicines that may lead to Soma drug interactions include:
  • Alcohol
  • Armodafinil (Nuvigil™)
  • Barbiturates, including:

    • Amobarbital (Amytal®)
    • Butalbital (Fioricet®, Fiorinal®)
    • Pentobarbital (Nembutal®)
    • Phenobarbital (Luminal®)
    • Secobarbital (Seconal®)
  • Benzodiazepines, including:

    • Alprazolam (Xanax®, Xanax® XR)
    • Chlordiazepoxide (Librium®, Limbitrol®, Librax®)
    • Clonazepam (Klonopin®)
    • Clorazepate (Tranxene®)
    • Diazepam (Valium®)
    • Estazolam (ProSom®)
    • Flurazepam (Dalmane®)
    • Lorazepam (Ativan®)
    • Midazolam (Versed®)
    • Temazepam (Restoril®)
    • Triazolam (Halcion®)
  • Carbamazepine (Carbatrol®, Epitol®, Equetro®, Tegretol®)
  • Certain antibiotics or antifungal medications, including:

    • Fluconazole (Diflucan®)
    • Ketoconazole (Nizoral®)
    • Miconazole
    • Isoniazid
    • Rifampin (Rifadin®)
  • Certain antidepressants, including:

    • Fluoxetine (Prozac®, Sarafem®)
    • Fluvoxamine (Luvox®, Luvox® CR)
    • Sertraline (Zoloft®)
    • Tranylcypromine (Parnate®)
  • Certain proton pump inhibitors (PPIs), including:

    • Esomeprazole (Nexium®)
    • Lansoprazole (Prevacid®)
    • Omeprazole (Prilosec®)
    • Rabeprazole (AcipHex®)
  • Delavirdine (Rescriptor®)
  • Gemfibrozil (Lopid®)
  • Modafinil (Provigil®)
  • Narcotics or opiates, such as morphine, oxycodone (OxyContin®), or hydrocodone (Lortab®, Vicodin®)
  • Phenytoin (Dilantin®, Phenytek®)
  • Sleep medications
  • Ticlopidine (Ticlid®).

Soma Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Soma is combined with any of the drugs listed above.
Alcohol
Combining alcohol with Soma can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may occur. It is best to avoid alcohol while taking Soma.
Armodafinil (Nuvigil)
The liver metabolizes Soma into meprobamate, a different drug with anti-anxiety properties. Armodafinil inhibits this process, increasing the level of Soma and decreasing the level of meprobamate in the blood. It is not known how this interaction might change the effectiveness or side effects of Soma.
Barbiturates
Taking a barbiturate with Soma can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may occur. Make sure to talk to your healthcare provider before taking Soma with a barbiturate.
Benzodiazepines
Combining Soma with a benzodiazepine can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may occur. Make sure to talk to your healthcare provider before taking Soma with a benzodiazepine.
Carbamazepine (Carbatrol, Epitol, Equetro, Tegretol)
The liver metabolizes Soma into meprobamate, a different drug with anti-anxiety properties. Carbamazepine increases this process, decreasing the level of Soma and increasing the level of meprobamate in the blood. It is not known how this interaction might change the effectiveness or side effects of Soma.
Certain Antibiotics or Antifungals
The liver metabolizes Soma into meprobamate, a different drug with anti-anxiety properties. Some antibiotics affect this process (either increasing or decreasing it, depending on the particular antibiotic). It is not known how these interactions might change the effectiveness or side effects of Soma.
Certain Antidepressants
The liver metabolizes Soma into meprobamate, a different drug with anti-anxiety properties. Some antidepressants inhibit this process, increasing the level of Soma and decreasing the level of meprobamate in the blood. It is not known how these interactions might change the effectiveness or side effects of Soma.
Certain Proton Pump Inhibitors (PPIs)
The liver metabolizes Soma into meprobamate, a different drug with anti-anxiety properties. Some proton pump inhibitors decrease this process, increasing the level of Soma and decreasing the level of meprobamate in the blood. It is not known how these interactions might change the effectiveness or side effects of Soma.
Delavirdine (Rescriptor)
The liver metabolizes Soma into meprobamate, a different drug with anti-anxiety properties. Delavirdine inhibits this process, increasing the level of Soma and decreasing the level of meprobamate in the blood. It is not known how this interaction might change the effectiveness or side effects of Soma.
Gemfibrozil (Lopid)
The liver metabolizes Soma into meprobamate, a different drug with anti-anxiety properties. Gemfibrozil inhibits this process, increasing the level of Soma and decreasing the level of meprobamate in the blood. It is not known how this interaction might change the effectiveness or side effects of Soma.
Modafinil (Provigil)
The liver metabolizes Soma into meprobamate, a different drug with anti-anxiety properties. Modafinil inhibits this process, increasing the level of Soma and decreasing the level of meprobamate in the blood. It is not known how this interaction might change the effectiveness or side effects of Soma.
Narcotics or Opiates
Combining an opiate or narcotic with Soma can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may occur. Make sure to talk to your healthcare provider before taking Soma with an opiate or narcotic.
Phenytoin (Dilantin, Phenytek)
The liver metabolizes Soma into meprobamate, a different drug with anti-anxiety properties. Phenytoin increases this process, decreasing the level of Soma and increasing the level of meprobamate in the blood. It is not known how this interaction might change the effectiveness or side effects of Soma.
Sleep Medications
Combining a sleep medication with Soma can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may occur. Make sure to talk to your healthcare provider before taking Soma with a sleep medication.
Ticlopidine (Ticlid)
The liver metabolizes Soma into meprobamate, a different drug with anti-anxiety properties. Ticlopidine inhibits this process, increasing the level of Soma and decreasing the level of meprobamate in the blood. It is not known how this interaction might change the effectiveness or side effects of Soma.

Final Thoughts on Soma Interactions

It is possible that not all Soma drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific drug interactions with Soma that may apply to you.
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